Avance Clinical to Present 'Decentralized Trials


Avance Clinical presents "Decentralized Trials - No Going Back" for Oracle Health Sciences Connect

Australia's leading CRO for biotech companies and Avance Clinical, Frost & Sullivan's Asia Pacific CRO Market Leadership Award winner, has been invited to speak at the Oracle Health Sciences Connect conference on the future of decentralized clinical trials.

Yvonne Lungershausen, CEO of Avance Clinical, shared the company's insights into the future of decentralized clinical trials (DCTs) and the technology and patient factors that will determine success. Avance Clinical leverages the full range of eClincial technologies to support clients who want DCTs or a location-based approach while leveraging advanced technologies such as ePro, eSource and eConsent.

"DCTs are fast becoming the new norm and this is an incredible opportunity for the drug development sector, as well as the diverse and remote patient populations who now have access to clinical trials," said Lungershausen.

"The pandemic spurred the acceleration in the adoption of decentralized clinical trial methods as participants stopped participating in trials and visiting clinics. Trials have put lives and significant investments at risk."

Yvonne Lungershausen said DCTs have significant benefits, including:

  • Reduce the burden of appointments and travel for patients and ensure convenient care at home.
  • Connecting Patients to Studies on a Global Scale - Patients who were otherwise inaccessible under more traditional study protocols are now available.

And she said that challenges include:

  • Missed person-to-person contact and continuity of patient care
  • Distribution of research products to more distant destinations
  • Monitoring of patient compliance and study procedures at home

The presentation will also cover advances in artificial intelligence (AI), machine learning, cloud computing, and blood self-collection devices that are revolutionizing the decentralized clinical trial process.

  • Wearable devices have enormous potential, regardless of whether they are worn on the body as a bracelet or as an adhesive tape. With AI embedded capabilities, these devices can remotely measure a patient's heart rate or metabolism. Connected to the cloud via secure networks, doctors can receive and analyze the data in real time.
  • Video calls and electronic reminders can improve patient compliance in studies and encourage participants to take their medication at the right time or include it in their electronic diary development.
  • Technologies are being developed that allow patient-centered sampling (self-drawing of samples) with devices that require a lancet and fingerprint while others do not, making clinical trials even more convenient.

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