Technology provides procedure efficiencies for congenital heart disease patients


WASHINGTON, DC (April 30, 2021) - Analysis of a new international registry shows the benefits of using a longer-covered stent for interventional procedures in patients with congenital heart disease with Sinus Venosus Atrial Septal Defect (SVASD). The study was unveiled today as groundbreaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2021 Scientific Sessions.

SVASD is a rare congenital heart disease in adults that allows blood to move from the systemic to the pulmonary circulation, causing excessive blood flow to the lungs. To date, open heart surgical repair has been the gold standard for managing this condition, but it is necessarily invasive. Covered stent implantation is a recently developed interventional procedure that can replace open heart surgery in some of these patients. However, according to the study's authors, there is no such thing as an "ideal stent" in which physicians frequently have to modify existing stents and often have to "piggyback" multiple stents, adding to the difficulty and potential complications of the procedure.

Researchers analyzed the results of the NuMED 10-Zig-Covered CP Stent (CCP), which is balloon expandable and intended for permanent implantation in patients. It is made of 0.013 "platinum-iridium wire that is arranged in a 10-zig pattern, laser welded at each connection, and then over-soldered with 24 carat gold. The 10-zig CCP stent has been used in 75 patients between the ages of Implanted from 12 centers at 11 and 75 years (median 45). The pre-procedure assessment included diagnostic catheterization in 30, 3D-printed models in 34 and virtual models in 13.

The results showed that 10-zig CCPs 7 to 8 centimeters provided a reliable SVASD closure with little need for additional stents. An additional stent was placed in 4/5 (80%) with 5 / 5.5 cm CCPs, 18/29 (62%) with 6 cm CCPs, 5/18 (28%) with 7 cm CCPs, 5/22 (23rd %) placed) with 7.5 / 8 cm CCPs and 0/1 with 11 cm CCP. The patients were followed from three weeks to five years.

"Our results show that the novel, longer stents represent a reliable technological advance that significantly reduces the need to implant additional stents. This helps to minimize many of the procedural risk factors and improve outcomes. More SVASD patients can get themselves undergo treatment. " This novel interventional procedure avoids the need for open heart surgery, "said Dr. Eric Rosenthal, lead investigator and congenital cardiologist for children and adults at Guy's and St. Thomas NHS Foundation Trust in London, England." These encouraging results support them the need for further research into the long-term benefits of 10-zig stents while expanding their use in patients with SVASD. "

The authors note that the longer covered stents are still being tested and require regulatory approval in most centers.

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About SCAI:

The Society for Cardiovascular Angiography and Interventions is a professional organization representing more than 4,000 professionals in invasive and interventional cardiology in approximately 75 countries. The mission of SCAI is to promote excellence in invasive / interventional cardiovascular medicine through medical training and representation as well as the further development of quality standards to improve patient care.

Further information on the scientific meetings of the SCAI 2021 can be found at https://scai.org/scai2021. Follow @SCAI on Twitter for the latest heart health news and use # SCAI2021 to keep up with the latest discussions.

Disclaimer: AAAS and EurekAlert! are not responsible for the correctness of the press releases published on EurekAlert! by contributing institutions or for the use of information via the EurekAlert system.


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